Lung & Respiratory Diseases

Tuberculosis (TB) remains a large-scale public health problem. Key global priorities for TB care is the timely detection of TB. Conventional and other methods are available for diagnosis of TB.Mycobacteriological culture and drug-susceptibility testing (DST) are slow and cumbersome, requiring sequential procedures for isolating mycobacteria from clinical specimens, identifying Mycobacterium tuberculosis complex (MTBC), and performing in vitro testing of strain susceptibility to anti-TB agents. During this time, patients may be in appropriately treated, drugresistant strains may continue to spread, and resistance may be amplified. GenExpert method is available in the market for the diagnosis of TB and Rifampicin resist-TB. These techniques are expensive and available at well-equipped laboratories at cities. But in India majority of TB patients are poor and/or living at rural/slum/tribal areas. So, that the highly economical POC - point of care diagnostic kit must be required. We have invented the best reagents for the diagnosis of TB and MDR-TB. Till date the work is carried out on glass slides. Now working on POC- based technology. This will be used for the development of simple, inexpensive technique for the diagnosis of death causing TB and MDR - TB. The kit is working on ligand receptor binding phenomenon. It’s a strip type which is precoated by the invented reagents, they are selective towards the type or stages of infection. The extracted bacteria in suitable reagents from the sample [sputum] or directly saliva/urine/blood, will bind to the developed reageants and results will be observed under blue LED /visible light.